Shatokhina S N, Shabalin V N
Urol Nefrol (Mosk). 1998 Mar-Apr(2):16-9.
It is known that when drying a drop of biological liquid under the action of osmotic forces acquires certain structure. The salts, which possess stronger osmotic potential, undergo crystallization in the center of the drop while protein components form the peripheral amorphic zone. In urolithiasis this process is impaired and crystallization of lithogenic salts occurs in the protein zone of a urine drop. This phenomenon discovered by the authors is designated as phenomenon of pathological crystallization of urine lithogenic salts. In nephrology and urology the above phenomenon may find application in diagnosis and control of urolithiasis activity, assessment of efficacy of the treatment conducted.
众所周知,当一滴生物液体在渗透力作用下干燥时会获得一定的结构。具有较强渗透势的盐在液滴中心结晶,而蛋白质成分则形成周边的无定形区域。在尿石症中,这个过程受到损害,致石盐在尿滴的蛋白质区域结晶。作者发现的这一现象被称为尿致石盐的病理结晶现象。在肾脏病学和泌尿外科学中,上述现象可应用于尿石症活动的诊断和控制、所进行治疗效果的评估。