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[直肠结肠切除术对液体平衡的影响——传统回肠造口术、回肠直肠吻合术和回肠肛管储袋手术的比较]

[Effect of proctocolectomy on fluid balance--comparison of conventional ileostomy, ileorectal anastomosis and ileoanal pouch operation].

作者信息

Brüwer M, Stern J, Schmidt-Gayk H, Senninger N, Herfarth C

机构信息

Chirurgische Universitätsklinik Münster.

出版信息

Z Gastroenterol. 1998 Mar;36(3):201-8.

PMID:9577903
Abstract

Total colectomy for ulcerative colitis (UC) and familiar adenomatous polyposis coli (FAP) is mainly performed as an ileoanal Pouch procedure (IAP). Alternatives are ileorectal anastomosis (IRA) and conventional proctocolectomy with Brooke ileostomy (CPS). The different surgical techniques may influence the excretion of water and electrolytes in stool and urine and may lead to a higher risk for urolithiasis. We investigated patients (12 IAP, 12 IRA and 8 CPS) several years after surgery and compared them to twelve normal controls. Total fecal and urinary output was collected at two consecutive days. Volume and electrolytes were determined in stool and urine. The risk for urinary stone formation was calculated by nomograms. Fecal volume and sodium (Na+) excretion was increased in all therapy groups compared to controls. IAP and IRA had significant less stool volume and Na+ excretion compared to CPS. Augmented fecal Na+ excretion was compensated by reduction of renal output after colectomy compared to controls. There were no significant differences in the daily urine volume between any groups. There was no urolithiasis in any groups. The nomograms showed a risk for all groups and controls to develop urinary stones.

摘要

溃疡性结肠炎(UC)和家族性腺瘤性息肉病(FAP)的全结肠切除术主要采用回肠肛管贮袋术(IAP)。替代方法是回肠直肠吻合术(IRA)和带布鲁克回肠造口术的传统直肠结肠切除术(CPS)。不同的手术技术可能会影响粪便和尿液中水电解质的排泄,并可能导致尿路结石风险增加。我们对术后数年的患者(12例IAP、12例IRA和8例CPS)进行了调查,并将他们与12名正常对照者进行比较。连续两天收集粪便和尿液的总量。测定粪便和尿液中的体积和电解质。通过列线图计算尿路结石形成的风险。与对照组相比,所有治疗组的粪便体积和钠(Na+)排泄量均增加。与CPS相比,IAP和IRA的粪便体积和Na+排泄量显著减少。与对照组相比,结肠切除术后粪便中Na+排泄量的增加通过肾脏排泄量的减少得到了补偿。各组之间的每日尿量没有显著差异。任何组均未出现尿路结石。列线图显示所有组和对照组都有发生尿路结石的风险。

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