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[结肠炎手术的变化。I:原发性手术治疗有标准吗?]

[Changes in colitis surgery. I: Is there a standard in primary surgical treatment?].

作者信息

Ecker K W, Kreissler-Haag D, Franz S, Feifel G

机构信息

Abteilung für Allgemeine Chirurgie, Abdominal- und Gefässchirurgie, Chirurgische Universitätsklinik Homburg/Saar.

出版信息

Zentralbl Chir. 1998;123(4):388-95.

PMID:9622899
Abstract

In a 15 years period surgery of ulcerative colitis expanded from ileostomy (IS) via Kock's pouch (KP) and ileoanal pouch (IAP) to ileorectal anastomosis (IRA). Interactions between availability of methods and frequency of operations are investigated retrospectively in order to establish an optimal primary procedure. With an overall amount of 80 operations the yearly operative frequency raised in correlation to the introduction of continence reconstructive procedures. As a consequence of this fact history of disease was shortened to less than 8 year and global colitis-associated morbidity markedly decreased. For patients readiness to undergo operation Kock's pouch was only important at the beginning (n = 9/11.3%). Most decisive was IAP (n = 49/61.3%) which could be realized last even in an one-stage-procedure with better early results due to improved patients conditions and simplified technical modifications. IRA (n = 7/8.8%) played only a limited role in the last years for selected patients, whereas IS (n = 15/18.8%) kept reserved for contraindications to reconstructive surgery. For all procedures operative complications decreased from 46.1% (12/26) to 11.0% (6/54) and lethality to 0%. Late complications were related to proctectomy (nerve damage) and construction of IAP (pouchitis in 34.8% and defunctioning of the pouch in 10.4%), whereas IRA was free of specific morbidity so far. Surgery of ulcerative colitis is characterized today by restoration of anal continence. The advantage of the changed surgical concept lies within the ability to perform colectomy at an earlier stage of the disease. Safe construction of IAP is the most important technical progress. Early operation of colitis and late morbidity of pouch justify (preliminary) IRA. Thus, surgical standard in colitis-surgery is defined more individually.

摘要

在15年的时间里,溃疡性结肠炎的手术方式从回肠造口术(IS)经科克贮袋(KP)和回肠肛管贮袋(IAP)发展到回肠直肠吻合术(IRA)。为确定最佳的初始手术方式,对手术方法的可用性与手术频率之间的相互关系进行了回顾性研究。在总共80例手术中,随着控便重建手术的引入,年手术频率呈上升趋势。由于这一事实,疾病史缩短至不到8年,与结肠炎相关的总体发病率显著降低。对于患者的手术意愿而言,科克贮袋仅在初期较为重要(9例/11.3%)。最具决定性的是回肠肛管贮袋(49例/61.3%),即使在一期手术中,由于患者状况改善和技术改良简化,它最终也能实现,且早期效果更好。回肠直肠吻合术(7例/8.8%)在过去几年中仅对特定患者发挥有限作用,而回肠造口术(15例/18.8%)则保留用于重建手术的禁忌情况。对于所有手术,手术并发症从46.1%(12/26)降至11.0%(6/54),死亡率降至0%。晚期并发症与直肠切除术(神经损伤)和回肠肛管贮袋的构建有关(贮袋炎发生率为34.8%,贮袋功能障碍发生率为10.4%),而到目前为止回肠直肠吻合术没有特定的发病率。如今,溃疡性结肠炎手术的特点是恢复肛门控便能力。手术理念改变的优势在于能够在疾病的早期阶段进行结肠切除术。回肠肛管贮袋的安全构建是最重要的技术进步。结肠炎的早期手术和贮袋的晚期发病率证明了(初步的)回肠直肠吻合术的合理性。因此,结肠炎手术的外科标准定义得更加个体化。

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