Quiñónez R E, Crawford M R
Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, USA.
Acta Otolaryngol. 1998 Jan;118(1):26-31. doi: 10.1080/00016489850155080.
The purpose of this investigation was to determine what types of changes occur in the distortion product otoacoustic emission (DPE) latency with increasing postconceptual age. These DPE latency changes were then described in relation to developmental changes in conductive and cochlear mechanisms in the neonate. Longitudinal DPE latency measurements were obtained from a single ear of 18 preterm neonates. DPEs were evoked at f2s of 3, 4 and 5 kHz. The longitudinal data revealed that DPE latency decreased as a function of postconceptual age for f2 of 3 and 4 kHz, but did not change significantly at 5 kHz. These findings suggest that (1) the conductive and/or cochlear system have not reached maturity in the preterm neonate, (2) DPE latency can be used to measure developmental changes in the auditory periphery, and (3) maturational changes need to be considered if DPE latency is used to identify auditory dysfunction in neonates.
本研究的目的是确定随着孕龄增加，畸变产物耳声发射（DPE）潜伏期会发生哪些类型的变化。然后，将这些DPE潜伏期变化与新生儿传导机制和耳蜗机制的发育变化联系起来进行描述。对18例早产新生儿的单耳进行了纵向DPE潜伏期测量。在3、4和5kHz的f2频率下诱发DPE。纵向数据显示，对于3kHz和4kHz的f2频率，DPE潜伏期随孕龄增加而缩短，但在5kHz时无显著变化。这些发现表明：（1）早产新生儿的传导系统和/或耳蜗系统尚未成熟；（2）DPE潜伏期可用于测量听觉外周的发育变化；（3）如果使用DPE潜伏期来识别新生儿的听觉功能障碍，则需要考虑成熟度变化。
