Quiñónez R E, Crawford M R
Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, USA.
Ann Otol Rhinol Laryngol. 1997 Sep;106(9):721-8. doi: 10.1177/000348949710600901.
The purposes of this investigation were to determine 1) if auditory peripheral maturity is present in the newborn; 2) if not, at what age maturational changes occur in the peripheral auditory system from preterm to full-term; and 3) how results of tests used to identify auditory dysfunction in neonates, such as distortion product otoacoustic emissions (DPEs) and auditory brain stem responses (ABRs), change during this period. Longitudinal DPE amplitude and ABR wave I latency measurements were obtained from a single ear of 18 preterm neonates. The DPEs were evoked at f2s of 2, 3, 4, and 5 kHz. The longitudinal data revealed that in general, DPE amplitude increased and ABR wave I latency decreased as a function of postconceptional age. These findings suggest that 1) the peripheral auditory system has not reached maturity in the preterm neonate; 2) maturational changes continue from preterm to full-term; and 3) these changes are reflected in ABR and DPE measurements.
1）新生儿是否具备听觉外周成熟度；2）若不具备，从早产儿到足月儿，外周听觉系统在什么年龄发生成熟变化；3）用于识别新生儿听觉功能障碍的测试结果，如畸变产物耳声发射（DPEs）和听觉脑干反应（ABRs），在此期间如何变化。对18名早产新生儿的单耳进行了纵向DPE振幅和ABR波I潜伏期测量。在2、3、4和5kHz的f2频率下诱发DPEs。纵向数据显示，一般来说，DPE振幅随着孕龄的增加而增加，ABR波I潜伏期随着孕龄的增加而缩短。这些发现表明：1）早产新生儿的外周听觉系统尚未成熟；2）从早产儿到足月儿，成熟变化持续存在；3）这些变化反映在ABR和DPE测量中。
