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The safety of pyrimethamine and sulfadoxine for the prevention of Pneumocystis carinii pneumonia.

作者信息

Teira R, Virosta M, Muñoz J, Zubero Z, Santamaría J M

机构信息

Sección de Enfermedades Infecciosas, Hospital de Basurto, Bilbao, Spain.

出版信息

Scand J Infect Dis. 1997;29(6):595-6. doi: 10.3109/00365549709035901.

Abstract

The medical records of 157 patients taking pyrimethamine-sulfadoxine for Pneumocystis carinii pneumonia prophylaxis were reviewed for assessment of safety and tolerance. 11 patients had experienced side effects, 7 (1 each: neutropenia, Stevens-Johnson, hepatic abnormalities; 2 each: subjective and hypersensitivity reactions) leading to a discontinuation of the drugs.

摘要

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