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肺栓塞排除:利用PIOPED数据对低概率情况的实用方法。肺栓塞诊断前瞻性研究。

Pulmonary embolism exclusion: a practical approach to low probability using the PIOPED data. Prospective Investigation of Pulmonary Embolism Diagnosis.

作者信息

Gray H W, Bessent R G

机构信息

Department of Nuclear Medicine, Royal Infirmary University NHS Trust, Alexandra Parade, Glasgow, UK.

出版信息

Eur J Nucl Med. 1998 Mar;25(3):271-6. doi: 10.1007/s002590050228.

DOI:10.1007/s002590050228
PMID:9580861
Abstract

A recent trend among physicians is the categorisation of lung scans as normal [excludes pulmonary embolism (PE)], high probability (confirms PE) and non-diagnostic (no judgement on PE risk). The low probability scan is therefore being eliminated as a functional category. This occasional survey contends that such an approach is misguided. Correction of the original PIOPED data with certain assumptions provides a more reproducible, albeit restricted, low probability scan category which excludes PE in 97% of cases in the low pre-test clinical category. Patients with a low probability scan with risk factors for PE (i.e. medium clinical risk) will require further investigation. More important, the very low probability scan category excludes PE in 98% of patients with low and more than 92% of patients with medium pre-test clinical likelihood. The demise of "low probability" is premature.

摘要

医生中最近的一个趋势是将肺部扫描分为正常(排除肺栓塞(PE))、高概率(确诊PE)和非诊断性(对PE风险无判断)。因此,低概率扫描作为一个功能类别正在被淘汰。这项偶然的调查认为这种方法是错误的。用某些假设对原始PIOPED数据进行校正,可提供一个更具可重复性(尽管有限)的低概率扫描类别,该类别在低预测试临床类别中97%的病例中排除了PE。有PE风险因素(即中等临床风险)的低概率扫描患者需要进一步检查。更重要的是,极低概率扫描类别在98%的低预测试临床可能性患者和92%以上的中等预测试临床可能性患者中排除了PE。“低概率”的消亡为时过早。

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