Leonard A, Gerber G B, Papworth D G, Decat G, Leonard E D, Deknudt G h
Mutat Res. 1976 Sep;36(3):319-32. doi: 10.1016/0027-5107(76)90242-6.
Dose-effect curves for X-irradiation in vitro were determined on cultured blood lymphocytes of four mammalian species-cow, goat, sheep and pig-having approximately the same number of chromosome arms, the same nuclear volume and the same DNA content. The data from cow, but not those from the other species, exhibited significant inhomogeneity between the experiments. On inspection the numerical yields appear not to differ greatly in the lower dose range. Evaluation of the parameters according to the quadratic law and the power law, however, demonstrate significant differences. Pig differs from the other species regardless of which presentation is chosen. For the power law a significant difference is also found between goat and sheep.
在体外对四种哺乳动物——牛、山羊、绵羊和猪——的培养血淋巴细胞测定了X射线照射的剂量效应曲线。这四种动物的染色体臂数大致相同、核体积相同且DNA含量相同。来自牛的数据在各实验之间表现出显著的不均匀性,但其他物种的数据并非如此。经检查,在较低剂量范围内,数值产量似乎差异不大。然而,根据二次定律和幂定律对参数进行评估时,结果显示存在显著差异。无论选择哪种呈现方式,猪与其他物种都不同。对于幂定律,山羊和绵羊之间也存在显著差异。