[弥漫性毒性甲状腺肿患者甲状腺组织中的脂质过氧化]
[Lipid peroxidation in thyroid tissue of people with diffuse toxic goiter].
作者信息
Rom-Boguslavskaia E S, Somova E V, Ovsiannikova T N, Diageleva E A, Karachentsev Iu I, Asaula V A
机构信息
Ukrainian Research Institute of Pharmacotherapy of Endocrine Diseases, Kharkov State University, Ukraine.
出版信息
Ukr Biokhim Zh (1978). 1997 Jul-Aug;69(4):111-4.
The processes of lipids free-radical oxidation in euthyroid and thyrotoxic tissue samples of human thyroid gland were studied. It was shown, that the content of TBA-active lipid peroxidation products was considerably increased in thyrotoxic tissue of the thyroid, and the activity of antioxidant enzymes (catalase, glutation peroxidase) was decreased in it. Possible mechanism of the tissue lipoperoxide alternation under conditions of the thyroid hyperfunction is discussed.
对人甲状腺正常甲状腺功能及甲状腺毒症组织样本中的脂质自由基氧化过程进行了研究。结果表明，甲状腺毒症组织中TBA活性脂质过氧化产物的含量显著增加，其中抗氧化酶（过氧化氢酶、谷胱甘肽过氧化物酶）的活性降低。讨论了甲状腺功能亢进情况下组织脂质过氧化物变化的可能机制。
Zotero 插件