Vandendael A, Kruger T F, de Villiers A, Menkveld R, Lombard C J
Department Obstetrics and Gynaecology, Tygerberg Hospital, Parow, South Africa.
Arch Androl. 1998 May-Jun;40(3):175-80. doi: 10.3109/01485019808987941.
The influence of antisperm antibodies in the female serum on fertilization and pregnancy rate in patients undergoing GIFT was assessed. A study group of 52 couples (69 cycles) with significant levels of antisperm antibodies in the female serum were compared to a control group of 749 couples (1185 cycles). Maternal serum or donor serum was used as growth medium supplement. The TAT test was performed for the detection of antisperm antibodies in the serum. Antisperm-antibody presence in female serum was associated with similar fertilization and pregnancy rates in a GIFT program compared to the control group. The type of serum used as growth medium supplement did not affect statistically the fertilization or pregnancy rate.
评估了女性血清中抗精子抗体对接受配子输卵管内移植（GIFT）患者受精及妊娠率的影响。将女性血清中抗精子抗体水平显著的52对夫妇（69个周期）作为研究组，与749对夫妇（1185个周期）的对照组进行比较。使用母体血清或供体血清作为生长培养基补充剂。采用TAT试验检测血清中的抗精子抗体。与对照组相比，女性血清中存在抗精子抗体在GIFT程序中与相似的受精和妊娠率相关。用作生长培养基补充剂的血清类型对受精或妊娠率没有统计学上的影响。
