Risse S, Fischer K, Schülke B
Nahrung. 1976;20(6):605-11. doi: 10.1002/food.19760200606.
Young rats were maintained on diets differing in fat content. The determination of certain parameters of the lipid and the energy metabolism in the liver showed that a high-fat diet resulted in a reduction of the stationary level of acetyl CoA, an increase in the concentration of acetoacetate and a reduction of the adenosine triphosphate content and the so-called energy charge. In case of intact respiratory chain phosphorylation, the oxygen consumption of the respective liver homogenates was simultaneously increased. The results obtained with a high-fat diet are indicative of the attainment of a metabolic state which seems to be typical of metabolic regulations in growing rats subjected to anabolic lipometabolism.
将幼鼠饲养在脂肪含量不同的饮食中。对肝脏中脂质和能量代谢的某些参数进行测定后发现，高脂饮食会导致乙酰辅酶A的稳定水平降低、乙酰乙酸浓度升高、三磷酸腺苷含量以及所谓的能荷降低。在完整呼吸链磷酸化的情况下，相应肝脏匀浆的耗氧量会同时增加。高脂饮食所获得的结果表明达到了一种代谢状态，这种状态似乎是处于合成代谢性脂肪代谢的生长大鼠典型的代谢调节特征。
