Bradshaw B G, Liu S S, Thirlby R C
Department of Anesthesia, Virginia Mason Medical Center, Seattle, WA 98111, USA.
J Am Coll Surg. 1998 May;186(5):501-6. doi: 10.1016/s1072-7515(98)00078-7.
Recent studies have suggested that critical pathways and standard order sets decrease hospital length of stay and improve quality of care. A recently conducted prospective, randomized study at our institution found that patients undergoing elective colon resections had earlier return of bowel function if perioperative epidural anesthesia and analgesia were provided. All patients in the study were also placed on a standardized perioperative regimen. We hypothesized that the standardized perioperative protocol used in this study contributed to early return of bowel function and hospital discharge compared with similar patients managed off protocol.
To test this hypothesis, we performed a case-controlled study comparing the hospital courses of 36 study patients to 36 control patients undergoing colorectal surgery by the same surgeons during the same calendar year. The distribution of types of operations and anesthetic techniques was similar in both groups.
As dictated by the protocol, all study patients had their nasogastric tubes removed, were started on a low fat liquid diet, and ambulated in the first postoperative day. Nasogastric tubes were removed in control patients and study patients 2.2 +/- 0.9 (mean value +/- SD) and 1.0 +/- 0.0 days postoperatively, respectively. Control patients were started on an oral diet, usually clear liquids, an average of 2.9 +/- 1.1 days postoperatively, a specific liquid diet was started 1.0 day postoperatively in study patients (p < 0.001). Return of bowel function, as determined by bowel tones, flatus, and bowel movements, occurred approximately 1 day earlier in study patients. Study patients were discharged 1 day sooner than control patients.
Our results suggest that the return of bowel function and the length of stay of patients undergoing colon surgery are improved if patients are entered into a standardized protocol that eliminates variation in intraoperative and postoperative anesthesia and postoperative surgical care. We believe these results can be reproduced in routine clinical surgery by having a clearly outlined protocol for perioperative care similar to that used in this study.
近期研究表明,关键路径和标准医嘱集可缩短住院时间并改善护理质量。我们机构最近进行的一项前瞻性随机研究发现,接受择期结肠切除术的患者若接受围手术期硬膜外麻醉和镇痛,肠功能恢复更早。该研究中的所有患者也都采用了标准化的围手术期治疗方案。我们假设,与未采用该方案治疗的类似患者相比,本研究中使用的标准化围手术期方案有助于肠功能的早期恢复和出院。
为验证这一假设,我们进行了一项病例对照研究,比较了36例研究患者与36例对照患者的住院过程,这些患者在同一年由相同的外科医生进行结直肠手术。两组的手术类型和麻醉技术分布相似。
按照方案要求,所有研究患者在术后第一天拔除鼻胃管,开始低脂流质饮食并下床活动。对照患者和研究患者分别在术后2.2±0.9(平均值±标准差)天和1.0±0.0天拔除鼻胃管。对照患者平均在术后2.9±1.1天开始口服饮食,通常为清流食,研究患者在术后1.0天开始特定的流质饮食(p<0.001)。根据肠鸣音、排气和排便情况确定,研究患者的肠功能恢复大约早1天。研究患者比对照患者提前1天出院。
我们的结果表明,如果患者采用标准化方案,消除术中、术后麻醉及术后外科护理的差异,结肠手术患者的肠功能恢复和住院时间会得到改善。我们相信,通过制定与本研究类似的清晰明确的围手术期护理方案,这些结果可在常规临床手术中重现。