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[脑瘫患儿的阻塞性睡眠呼吸暂停]

[Obstructive sleep apnea in children with cerebral palsy].

作者信息

Shintani T, Asakura K, Ishi K, Yoshida M, Kataura A, Ogasawara H

机构信息

Department of Otolaryngology, Sapporo Medical University, School of Medicine.

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 1998 Mar;101(3):266-71. doi: 10.3950/jibiinkoka.101.266.

Abstract

To determine the etiology of obstructive sleep apnea (OSA) in children with cerebral palsy (CP), a survey using a questionnaire was conducted on parents of 233 CP children (1-5 years old, mean age: 2.7) and on those of 343 control children during a routine medical check-up at the age of three. The prevalence of habitual snoring and nasal obstruction was 63 and 20% in CP children, which were significantly higher than in control children. Sleep apnea episodes and stridor were noted in 19.7 and 15.4% of CP children. A screening sleep study was performed using Apnomonitor II and a pulseoximeter (Pulsox 5) in 48 CP children whose questionnaires revealed habitual snoring and sleep apnea, and it was found that 27 and 58% of the children had on apnea-hypopnea index (AHI) of greater than 5 and a low level of SaO2 (LSaO2) of less than 85%, respectively. When another 10 CP children visited our hospital for treatment of severe OSA, precise evaluations including pharyngeal pressure and fiberscopic examination during sleep as well as a sleep study using an inductive prezysmograph (Respigraph) were performed. Adenoid and/or tonsillar hypertrophy were noted in only 4 children, and the main cause of sleep apnea in the other 6 children was pharyngeal collapse at the lingual base. Their OSA was successfully treated by adenotonsillectomy in 2 children, adenotomy in 2 children, UPPP and lingualplasty in 1 child, tracheostomy in 2 children, and nasal CPAP in 1 child. Before treatment of OSA in CP children, precise evaluation is recommended in order to perform appropriate treatment.

摘要

为确定脑瘫(CP)患儿阻塞性睡眠呼吸暂停(OSA)的病因,在三岁常规体检时,对233名CP患儿(1 - 5岁,平均年龄:2.7岁)的家长以及343名对照儿童的家长进行了问卷调查。CP患儿习惯性打鼾和鼻塞的患病率分别为63%和20%,显著高于对照儿童。19.7%的CP患儿出现睡眠呼吸暂停发作,15.4%的患儿出现喘鸣。对48名问卷显示有习惯性打鼾和睡眠呼吸暂停的CP患儿,使用Apnomonitor II和脉搏血氧仪(Pulsox 5)进行了筛查睡眠研究,发现分别有27%和58%的患儿呼吸暂停低通气指数(AHI)大于5且动脉血氧饱和度低水平(LSaO2)低于85%。另外10名因重度OSA来我院治疗的CP患儿,进行了包括睡眠期间咽部压力和纤维镜检查以及使用感应式呼吸描记器(Respigraph)进行睡眠研究在内的精确评估。仅4名患儿发现腺样体和/或扁桃体肥大,其他6名患儿睡眠呼吸暂停的主要原因是舌根处咽部塌陷。2名患儿通过腺样体扁桃体切除术、2名患儿通过腺样体切除术、1名患儿通过悬雍垂腭咽成形术和舌成形术、2名患儿通过气管切开术、1名患儿通过鼻持续气道正压通气成功治疗了OSA。在治疗CP患儿的OSA之前,建议进行精确评估以便进行适当治疗。

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