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[评估外阴癌联合治疗及放射治疗的疗效]

[Evaluating the efficiency of combined and radiation treatment of vulvar cancer].

作者信息

Pereslegin I A, Rybakov Iu N, Nikitina T P, Semko V F

机构信息

Russian State Medical University.

出版信息

Vestn Rentgenol Radiol. 1998 Jan-Feb(1):36-9.

PMID:9584652
Abstract

The outcomes of radiation treatment of 70 patients with Stage I-II vulvar cancer are analyzed. Combined treatment was used in 10 patients (3 and 7 patients had Stage I and II, respectively), combined radical radiation therapy was applied in 21 patients (Stage II), split-course gamma-teletherapy was employed in 28 patients (6 and 22 patients with Stages II and III, respectively) and 3 females had short-range X-ray therapy. Palliative radiation therapy was performed in 8 patients with Stage III tumors. Complete clinical tumor resolution was achieved in 16 (57%) patients receiving gamma-teletherapy, 15 (71.4%) and in all three women having short-range X-ray therapy. It is recommended that patients with vulvar cancer should receive split-course radiation, which yields good late treatment results and prevents from significant local radiation reactions and complications. Early diagnosis and timely use of combined treatment provide best treatment results in patients with vulvar cancer and in those with other malignant neoplasms.

摘要

分析了70例I-II期外阴癌患者的放射治疗结果。10例患者采用联合治疗(I期3例,II期7例),21例患者采用联合根治性放射治疗(II期),28例患者采用分段伽马远距离治疗(II期6例,III期22例),3例女性采用短距离X线治疗。对8例III期肿瘤患者进行了姑息性放射治疗。接受伽马远距离治疗的16例(57%)患者、15例(71.4%)以及接受短距离X线治疗的所有3例女性患者实现了临床肿瘤完全消退。建议外阴癌患者接受分段放射治疗,其后期治疗效果良好,并可预防严重的局部放射反应和并发症。早期诊断并及时采用联合治疗可使外阴癌患者及其他恶性肿瘤患者获得最佳治疗效果。

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