大鼠血浆和肠激肽释放酶的分子量
The molecular weights of plasma and intestinal kallikreins in rats.
作者信息
Zeitlin I J, Singh Y N, Lembeck F, Theiler M
出版信息
Naunyn Schmiedebergs Arch Pharmacol. 1976 May;293(2):159-61. doi: 10.1007/BF00499221.
PMID:958504
Abstract
- The molecular weights of kallikreins of rat intestine and rat plasma have been estimated using gel filtration. 2. Extracts of pooled tissue from rat jejunum, ileum, caecum and colon activated by autolytic processes gave a single peak of kallikrein activity with a molecular weights of 33000. 3. Acid-activated rat plasma gave two peaks of kallikrein activity with molecular weight of 125000 and 61500. 4. Rat intestinal tissue contains a kinin forming enzyme having a molecular weight similar to those of glandular kallikreins and different from those of the rat plasma kallikreins.
摘要
- 已使用凝胶过滤法估算了大鼠肠道和大鼠血浆激肽释放酶的分子量。2. 来自大鼠空肠、回肠、盲肠和结肠的合并组织提取物经自溶过程激活后，激肽释放酶活性呈现单峰，分子量为33000。3. 酸激活的大鼠血浆产生了两个激肽释放酶活性峰，分子量分别为125000和61500。4. 大鼠肠道组织含有一种激肽形成酶，其分子量与腺激肽释放酶相似，与大鼠血浆激肽释放酶不同。
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