Mizuno K, Nagamatsu M, Hattori N, Yamamoto M, Goto H, Kuniyoshi K, Sobue G
Department of Neurology, Nagoya University School of Medicine, Japan.
Muscle Nerve. 1998 Jun;21(6):805-8. doi: 10.1002/(sici)1097-4598(199806)21:6<805::aid-mus16>3.0.co;2-r.
We present 3 patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with extensive and diffuse hypertrophy of the nerve roots and peripheral nerves. They exhibited slowly progressive sensory impairment and distally predominant limb weakness and muscular atrophy, and markedly enlarged palpable nerve trunks. They responded beneficially to corticosteroid. Magnetic resonance imaging demonstrated diffuse and extensive hypertrophy of the peripheral nerves in the four limbs and the spinal nerve roots, with gadolinium enhancement in the nerve roots but not in the peripheral nerves. These patients were considered to have a hypertrophic variant of CIDP.
我们报告3例慢性炎症性脱髓鞘性多发性神经根神经病（CIDP）患者，其神经根和周围神经广泛弥漫性肥大。他们表现出缓慢进展的感觉障碍、以肢体远端为主的肌无力和肌肉萎缩，以及可触及的明显增粗的神经干。他们对皮质类固醇治疗反应良好。磁共振成像显示四肢周围神经和脊神经根弥漫性广泛肥大，神经根有钆增强，但周围神经无增强。这些患者被认为患有CIDP的肥大变异型。
