García Ruiz P J, Sánchez del Río M, Cenjor Español C, Sanabria Brassart J, Sánchez Bernardos V, Astarloa Gómez R, García de Yébenes J
Servicio de Neurología, Fundación Jiménez Díaz, Madrid.
Rev Clin Esp. 1998 Mar;198(3):156-8.
Adduction spastic dystonia (SD) is currently considered a focal dystonia involving laryngeal muscles. SD is one of the most poorly known focal dystonias. We reviewed our experience with twentynine patients with adduction SD and compared the clinical and epidemiologic variables with the other focal dystonias studied at our institution in the last five years (132 patients). Mean age of patients (47.2 +/- 13 years), sex, clinical course in years (5.7 +/- 5) and presence of circadian fluctuations did not differ significantly from those observed in patients with other focal dystonias. Likewise, there were no significant differences regarding the presence of a family history of dystonia, essential tremor, or stuttering. Our results confirm the similarity of the clinical and epidemiologic data of SD with the other focal dystonias. All patients with SD were treated with a local injection of botulinum toxin. A total of 108 treatments were performed, 41 with a visually guided transoral technique and 67 with a percutaneous technique. The transoral technique was effective in all cases (41/41) but not all treatments with the percutaneous technique were effective (53/67). Three patients required the shift to the transoral procedure to achieve enough symptomatic alleviation.
内收型痉挛性肌张力障碍(SD)目前被认为是一种累及喉部肌肉的局灶性肌张力障碍。SD是最鲜为人知的局灶性肌张力障碍之一。我们回顾了29例内收型SD患者的治疗经验,并将其临床和流行病学变量与本机构在过去五年中研究的其他局灶性肌张力障碍患者(132例)进行了比较。患者的平均年龄(47.2±13岁)、性别、病程(5.7±5年)以及昼夜波动情况与其他局灶性肌张力障碍患者相比无显著差异。同样,在肌张力障碍、特发性震颤或口吃家族史方面也无显著差异。我们的结果证实了SD与其他局灶性肌张力障碍在临床和流行病学数据上的相似性。所有SD患者均接受了肉毒杆菌毒素局部注射治疗。共进行了108次治疗,其中41次采用视觉引导经口技术,67次采用经皮技术。经口技术在所有病例中均有效(41/41),但并非所有经皮技术治疗都有效(53/67)。3例患者需要改用经口技术以获得足够的症状缓解。