[Role of the lawc(p1) mutation in the regulation of the white locus expression in Drosophila].

The lawcp1 mutation of the leg-arista-wing complex (lawc) gene alters expression of three proneural loci: achaete, scute, and cut. In combination with the product of the zeste (z) gene, the product of the lawc gene regulates expression of the white (w) gene. The -w B3 mutation was genetically analyzed in compounds with various z and w mutations and dominant mutations modifying the z-w interaction. The results showed that lawcp1 can enhance the transvection effect. The lawc gene was assumed to regulate expression of the white locus at the level of chromatin condensation.