Yang H, Jiang Y, Wu Z
Ophthalmology Department, Second Affiliated Hospital, Hunan Medical University, Changsha.
Zhonghua Yan Ke Za Zhi. 1996 Jul;32(4):272-6.
To observe the features of the changes of color pattern electroretinogram (CP-ERG) in early primary open-angle glaucoma (POAG).
The detection and analyses of CP-ERGs in 29 patients (48 eyes) with POAG, 10 patients (16 eyes) with ocular hypertension and 33 age-matched normal volunteers (48 eyes) were made.
The changes of CP-ERG in early POAG included reduction of amplitudes of P1 and N2 waves, prolongation of the peak times of red/black N2 and blue/black P1 waves. Part of the patients with ocular hypertension had the amplitude of N2 wave reduced. Five factors including the amplitude of blue/black N2 wave, the amplitudes of red/black P1 and N2 waves, the peak time of red/black N2 wave and the white/black P1 to N2 wave amplitude ratio from CP-ERG which are significantly correlated to the diagnosis of early POAG were selected by the multiple factor stepwise discriminatory analysis, and the stepwise discriminatory function was set up.
CP-ERG is a useful method in detecting the retinal functions in early POAG, and is helpful to its early diagnosis.
观察原发性开角型青光眼（POAG）早期彩色视觉诱发电位（CP-ERG）的变化特征。
对29例（48只眼）POAG患者、10例（16只眼）高眼压症患者及33例年龄匹配的正常志愿者（48只眼）进行CP-ERG检测与分析。
POAG早期CP-ERG的变化包括P1波和N2波振幅降低，红/黑N2波和蓝/黑P1波峰时延长。部分高眼压症患者N2波振幅降低。通过多因素逐步判别分析，从CP-ERG中筛选出蓝/黑N2波振幅、红/黑P1波和N2波振幅、红/黑N2波峰时以及白/黑P1与N2波振幅比5个与POAG早期诊断显著相关的因素，并建立逐步判别函数。
CP-ERG是检测POAG早期视网膜功能的一种有用方法，有助于其早期诊断。
