Aboul-Dahab O
Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.
Egypt Dent J. 1993 Jul;39(3):511-8.
Several effectors and mediators of inflammation have been identified as principle factors in periodontal disease progression. It has been reported that topical and systemic application of flurbiprofen (non-steroidal anti-inflammatory drug) reduced the rate of alveolar bone loss as well as signs of gingival inflammation. Twenty rapidly progressive as well as juvenile periodontitis patients were included in the present study. Results of the present study showed a significant reduction in pocket depth & gingival index in the experimental group over the control group. Radiographs revealed more bone fill in the experimental group over the control group.
几种炎症效应器和介质已被确定为牙周病进展的主要因素。据报道，局部和全身应用氟比洛芬（非甾体抗炎药）可降低牙槽骨吸收速率以及牙龈炎症迹象。本研究纳入了20例快速进展性牙周炎患者和青少年牙周炎患者。本研究结果显示，与对照组相比，实验组的牙周袋深度和牙龈指数显著降低。X线片显示，与对照组相比，实验组有更多的骨填充。
