一种三嗪染料，汽巴克隆蓝F3GA，可降低耐甲氧西林金黄色葡萄球菌对苯唑西林的耐药水平。
A triazine dye, cibacron blue F3GA, decreases oxacillin resistance levels in methicillin-resistant Staphylococcus aureus.
作者信息
Shirai C, Sugai M, Komatsuzawa H, Ohta K, Yamakido M, Suginaka H
机构信息
Department of Internal Medicine II, Hiroshima University School of Medicine, Japan.
出版信息
Antimicrob Agents Chemother. 1998 May;42(5):1278-80. doi: 10.1128/AAC.42.5.1278.
Abstract
Cibacron blue F3GA (CB) was found to reduce the MIC of oxacillin for methicillin-resistant Staphylococcus aureus (MRSA). This effect was not observed with methicillin-susceptible S. aureus. CB alters the resistance level of MRSA through a factor(s) other than mecA-related products, major autolysins, or femAB products. The exact target(s) of CB in causing the effect is unknown.
摘要
发现汽巴克隆蓝F3GA（CB）可降低耐甲氧西林金黄色葡萄球菌（MRSA）对苯唑西林的最低抑菌浓度（MIC）。而甲氧西林敏感的金黄色葡萄球菌未观察到这种效应。CB通过与mecA相关产物、主要自溶素或femAB产物不同的因素改变MRSA的耐药水平。CB产生这种效应的确切靶点尚不清楚。
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Antimicrob Agents Chemother. 1996 Dec;40(12):2680-5. doi: 10.1128/AAC.40.12.2680.
2
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3
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J Bacteriol. 1993 Mar;175(6):1612-20. doi: 10.1128/jb.175.6.1612-1620.1993.
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