在急性视网膜中央静脉阻塞中，通过省略前房角镜检查而遗漏房角新生血管形成的风险。
The risk of missing angle neovascularization by omitting screening gonioscopy in acute central retinal vein occlusion.
作者信息
Browning D J, Scott A Q, Peterson C B, Warnock J, Zhang Z
机构信息
Charlotte Eye, Ear, Nose, and Throat Associates, North Carolina, USA.
出版信息
Ophthalmology. 1998 May;105(5):776-84. doi: 10.1016/S0161-6420(98)95014-X.
OBJECTIVE
The purpose of the study was to determine whether angle neovascularization can occur without pupillary margin neovascularization in central retinal vein occlusion (CRVO).
DESIGN
The study design was a prospective study of the main question and a retrospective study of ancillary issues.
PARTICIPANTS
The authors examined 105 eyes of 100 patients with CRVO having clinical evidence of ischemia between July 1, 1986, and March 18, 1996.
INTERVENTION
The authors looked for iris and angle neovascularization with both undilated slit-lamp biomicroscopy and Zeiss four-mirror gonioscopy.
MAIN OUTCOME MEASURES
The presence of anterior segment neovascularization was measured.
RESULTS
Of 34 eyes developing anterior segment neovascularization, 4 (12%) developed angle neovascularization without pupillary margin neovascularization over a mean follow-up of 2.2 +/- 2.4 standard deviation years.
CONCLUSIONS
Angle neovascularization can occur without pupillary margin involvement in CRVO, implying the necessity of screening gonioscopy and supporting the Central Vein Occlusion Study conclusion (based on a photographic technique not used clinically).
目的
本研究旨在确定在视网膜中央静脉阻塞（CRVO）中，房角新生血管是否能在没有瞳孔缘新生血管的情况下发生。
设计
本研究设计为对主要问题的前瞻性研究以及对辅助问题的回顾性研究。
参与者
作者检查了1986年7月1日至1996年3月18日期间100例有缺血临床证据的CRVO患者的105只眼。
干预
作者通过未散瞳的裂隙灯生物显微镜检查和蔡司四镜房角镜检查来寻找虹膜和房角新生血管。
主要观察指标
测量眼前段新生血管的存在情况。
结果
在34只发生眼前段新生血管的眼中，4只（12%）在平均随访2.2±2.4标准差年期间出现了没有瞳孔缘新生血管的房角新生血管。
结论
在CRVO中，房角新生血管可在无瞳孔缘受累的情况下发生，这意味着需要进行房角镜筛查，并支持中央静脉阻塞研究的结论（基于一种未在临床使用的摄影技术）。
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