Rodgers A L
Department of Chemistry, University of Cape Town.
S Afr Med J. 1998 Apr;88(4):448-51.
This study was undertaken to identify a South African mineral water containing relatively high concentrations of calcium and magnesium and to investigate its effect on urinary biochemical and physicochemical risk factors associated with calcium oxalate kidney stone formation.
The study followed a change-over design in which each subject followed a randomised sequence of three water-drinking protocols involving their normal diet, a calcium and magnesium-rich mineral water and a mineral water deficient in these elements.
University of Cape Town.
54 volunteers without any previous history of stone disease (27 men, 27 women) in the age group 21-35 years and 31 with a history of calcium oxalate kidney stones (24 men, 7 women) in the age group 25-45 years participated in the study.
Both mineral waters favourably altered several risk factors. However, the effect of the calcium- and magnesium-rich water was shown to be significantly greater as it altered a larger number of these factors and induced several unique changes that were not achieved by the other water.
The risk of calcium oxalate stone formation can be significantly reduced by consumption of mineral water which is rich in calcium and magnesium.
本研究旨在确定一种钙和镁含量相对较高的南非矿泉水，并研究其对与草酸钙肾结石形成相关的尿液生化和物理化学风险因素的影响。
该研究采用了交叉设计，即每个受试者遵循三种饮水方案的随机顺序，这三种方案包括他们的正常饮食、富含钙和镁的矿泉水以及缺乏这些元素的矿泉水。
开普敦大学。
54名年龄在21 - 35岁且无结石病史的志愿者（27名男性，27名女性）以及31名年龄在25 - 45岁且有草酸钙肾结石病史的志愿者（24名男性，7名女性）参与了该研究。
两种矿泉水均有利地改变了几个风险因素。然而，富含钙和镁的水的效果显著更大，因为它改变了更多此类因素，并引发了其他水未实现的一些独特变化。
饮用富含钙和镁的矿泉水可显著降低草酸钙结石形成的风险。
