Dal Cin P, Lipcsei G, Hermand G, Boniver J, Van den Berghe H
Center for Human Genetics, University of Leuven, Belgium.
Cancer Genet Cytogenet. 1998 May;103(1):68-70. doi: 10.1016/s0165-4608(97)00350-6.
Cytogenetic analysis of a congenital mesoblastic nephroma (CMN) in a 1-month-old boy showed a 48,XY, +10, +11 karyotype. In this particular tumor type, chromosomal changes are found in almost all cases. Among the numerical changes, trisomy 11 stands out, whereas involvement of the long arm of chromosome 15 may be a nonrandomly occurring structural change.
对一名1个月大男婴的先天性中胚层肾瘤（CMN）进行细胞遗传学分析，结果显示其核型为48,XY, +10, +11。在这种特定的肿瘤类型中，几乎在所有病例中都发现了染色体变化。在数量变化中，11号染色体三体最为突出，而15号染色体长臂的受累可能是一种非随机发生的结构变化。
