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铜绿假单胞菌中的组成型胆碱转运

Constitutive choline transport in Pseudomonas aeruginosa.

作者信息

Lucchesi G I, Pallotti C, Lisa A T, Domenech C E

机构信息

Departamento de Biología Molecular, Universidad Nacional de Río Cuarto, Córdoba, Argentina.

出版信息

FEMS Microbiol Lett. 1998 May 1;162(1):123-6. doi: 10.1111/j.1574-6968.1998.tb12988.x.

Abstract

Pseudomonas aeruginosa has a choline uptake system which is expressed in bacteria grown in the presence of succinate and ammonium chloride as the carbon and nitrogen source, respectively. This system obeys Michaelis-Menten kinetics with an apparent Km value of 53 microM; its activity is not inhibited by high osmolarities in the medium but is partially inhibited by choline metabolites such as betaine and dimethylglycine.

摘要

铜绿假单胞菌具有一种胆碱摄取系统,该系统在分别以琥珀酸盐和氯化铵作为碳源和氮源培养的细菌中表达。此系统遵循米氏动力学,表观 Km 值为 53 微摩尔;其活性不受培养基中高渗透压的抑制,但会被胆碱代谢物如甜菜碱和二甲基甘氨酸部分抑制。

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