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锝-99m植酸盐闪烁扫描术在酒精性泡沫样变性诊断中的应用价值

Usefulness of scintigraphy with Tc-99m phytate for the diagnosis of alcoholic foamy degeneration.

作者信息

Shiomi S, Sasaki N, Yokogawa T, Kawada N, Sakaguchi H, Nakajima S, Kuroki T, Kawabe J, Ochi H

机构信息

Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.

出版信息

Clin Nucl Med. 1998 May;23(5):302-4. doi: 10.1097/00003072-199805000-00007.

Abstract

PURPOSE

Alcoholic foamy degeneration (AFD) is a liver disease causing temporary hepatocyte dysfunction. The prognosis is usually good, but liver biopsy is needed for diagnosis. We report the usefulness of liver-spleen scintigraphy with the radiocolloid Tc-99m phytate for the diagnosis of AFD.

PATIENTS AND METHODS

We used liver scintigraphy with Tc-99m phytate to study three patients with AFD diagnosed on the basis of findings from a liver biopsy.

RESULTS

Liver-spleen scintigraphy showed hepatomegaly and splenomegaly, and bone marrow was visible, but radioisotope uptake by the liver was uniform.

CONCLUSIONS

This pattern of scintigraphic findings is different from that reported for patients with alcoholic fatty livers or severe alcoholic hepatitis, and seems to be specific for AFD.

摘要

目的

酒精性泡沫样变性(AFD)是一种导致肝细胞暂时性功能障碍的肝脏疾病。其预后通常良好,但诊断需要进行肝活检。我们报告了用放射性胶体锝-99m植酸盐进行肝脾闪烁扫描对AFD诊断的实用性。

患者和方法

我们用锝-99m植酸盐进行肝脏闪烁扫描,研究了3例根据肝活检结果诊断为AFD的患者。

结果

肝脾闪烁扫描显示肝脏肿大和脾脏肿大,且可见骨髓,但肝脏的放射性同位素摄取均匀。

结论

这种闪烁扫描结果模式与酒精性脂肪肝或严重酒精性肝炎患者的报告不同,似乎是AFD所特有的。

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