Drum D E, Beard J O
J Nucl Med. 1978 Feb;19(2):154-60.
The relationships between scintigraphic features and clinical alcoholism were studied by review of 2,406 liver scintiphotos. Two distinct patterns were significantly associated with alcoholism: (a) heterogeneous distribution of radiocolloid in the liver, and (b) jointly increased uptake of tracer by the spleen and vertebral bone marrow. A total of 13 overall patterns were found to distinguish, with considerable reliability, alcoholics from all other patients. This finding reflects the frequency with which alcohol abuse is associated with hepatic dysfunction in hospital patients. These observations indicate an important role for the nuclear medicine physician in detection of alcoholism among patients referred for liver-spleen imaging, and they form a basis for comparison with the diagnostic efficacy of other methods of evaluating diffuse liver diseases.
通过回顾2406例肝脏闪烁扫描照片,研究了闪烁扫描特征与临床酒精中毒之间的关系。两种不同的模式与酒精中毒显著相关:(a)肝脏中放射性胶体分布不均,(b)脾脏和椎骨骨髓对示踪剂的摄取共同增加。总共发现13种总体模式能够以相当高的可靠性区分酗酒者与所有其他患者。这一发现反映了医院患者中酒精滥用与肝功能障碍相关的频率。这些观察结果表明核医学医生在对进行肝脾成像的患者进行酒精中毒检测中具有重要作用,并且它们构成了与评估弥漫性肝病的其他方法的诊断效力进行比较的基础。