Kinney W C, Wallace R C, Ross J S, Kinney S E, Hamid M A
Department of Otolaryngology, The Cleveland Clinic Foundation, Ohio, USA.
Am J Otol. 1998 May;19(3):341-4.
To evaluate the magnetic resonance imaging results (MRI) of patients with electronystagmography (ENG) suggestive of central vestibular dysfunction and to determine if MRI abnormalities correlate with ENG findings.
Retrospective blinded case review.
A regional neurotology center.
Patients with ENG suggesting central vestibular dysfunction were identified (n = 30). An age-matched group of patients with normal ENG results were used as controls (n = 28).
MRI abnormalities in cerebellum, brain stem, cerebellar peduncles, and central ENG findings.
Twenty-one patients with abnormal MRI results of the vestibular pathway were found, 15 with abnormal and 6 with normal ENG results. MRI correlation with ENG findings has a better predictive value in older patients than in younger patients. Sixteen patients had MRI evidence of vascular compression, seven of whom had abnormal and nine of whom had normal ENG results.
This study suggests that a detailed review of MRI images of the vestibular pathway is warranted, and, in patients with central ENG abnormalities, MRI may support the diagnosis of central vestibular dysfunction. MRI cannot support central vestibular dysfunction caused by vascular compression.
评估眼震电图（ENG）提示中枢性前庭功能障碍患者的磁共振成像（MRI）结果，并确定MRI异常是否与ENG检查结果相关。
回顾性盲法病例分析。
一个地区性神经耳科学中心。
确定了ENG提示中枢性前庭功能障碍的患者（n = 30）。将年龄匹配的ENG结果正常的患者作为对照组（n = 28）。
小脑、脑干、小脑脚的MRI异常以及中枢性ENG检查结果。
发现21例前庭通路MRI结果异常的患者，其中15例ENG结果异常，6例ENG结果正常。MRI与ENG检查结果的相关性在老年患者中比在年轻患者中具有更好的预测价值。16例患者有血管压迫的MRI证据，其中7例ENG结果异常，9例ENG结果正常。
本研究表明，有必要对前庭通路的MRI图像进行详细评估，并且在中枢性ENG异常的患者中，MRI可能有助于中枢性前庭功能障碍的诊断。MRI不能支持血管压迫导致的中枢性前庭功能障碍。
