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清醒或麻醉猫在缺氧或高碳酸血症期间的呼吸模式。

Pattern of breathing during hypoxia or hypercapnia of the awake or anesthetized cat.

作者信息

Gautier H

出版信息

Respir Physiol. 1976 Aug;27(2):193-206. doi: 10.1016/0034-5687(76)90074-8.

DOI:10.1016/0034-5687(76)90074-8
PMID:959676
Abstract

The breathing patterns during hypoxia and hypercapnia are similar in anesthetized cats but are qualitatively different in awake cats. The differences seen in the awake animals can be explained by either the central depressive effect of hypoxia or by a specific effect of hypercapnia on supra-pontine structures. The Breuer-Hering reflex sensitivity, i.e. the VT-TI relationship, appears, in the awake cat, quite similar to that recently described in man. The inspiratory activity is shown to be controlled by mechanisms dependent on the nature of the respiratory stimulation. The recent model proposed for the control of inspiration during anesthesia must be modified to account for the results observed in awake animal.

摘要

在麻醉猫中,低氧和高碳酸血症时的呼吸模式相似,但在清醒猫中则存在质的差异。清醒动物中观察到的差异,要么可以用低氧的中枢抑制作用来解释,要么可以用高碳酸血症对脑桥上结构的特定作用来解释。在清醒猫中,布雷尔-黑林反射敏感性,即潮气量与吸气时间的关系,似乎与最近在人类中描述的情况非常相似。吸气活动被证明受取决于呼吸刺激性质的机制控制。为解释麻醉期间的吸气控制而提出的最新模型必须加以修改,以解释在清醒动物中观察到的结果。

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