Mikol F, Stagel M, Mikol J
Rev Neurol (Paris). 1976 May;132(5):325-41.
The authors reported five cases of eyelid ptosis with progesssive external ophthalmoplegia. They emphasize infra-clinic diffusion, fatigability and variability impairment of extra-ocular muscles; coexistence of myogenic E.M.G. and single potential recurring at high frequency in the same patient; mitochondrial abnormalities in type I fibers, intense oxydative activity in superior oblique muscle and normal motor end-plates.
作者报告了5例伴有进行性眼外肌麻痹的眼睑下垂病例。他们强调眼外肌的临床下扩散、易疲劳性和变异性损害;同一患者存在肌源性肌电图和高频反复出现的单电位;I型纤维中的线粒体异常、上斜肌中的强烈氧化活性以及正常的运动终板。