Yamaguchi Y, Dobashi N, Usui N, Kobayashi T, Nakamura T, Takasaki N, Kato A, Watanabe H, Saito T, Tajima N, Kuraishi Y
Department of Hematology/Oncology, Jikei University Hospital.
Rinsho Ketsueki. 1998 Apr;39(4):297-301.
A 69-year-old man who initially presented with lumbago developed heart failure during an MRI scan on the day of admission. A chest X-ray showed cardiomegaly and bilateral pleural effusion. Echocardiogram and computed tomography (CT) scan of the chest revealed a large tumor mass encompassing the heart with much pericardial effusion was demonstrated. The cytology of the effusion obtained by pericardiocentesis was consistent with non-Hodgkin's lymphoma, diffuse large B cell type. As CT scans of the abdomen and pelvis were negative, he was considered to have primary cardiac lymphoma. Although he responded remarkably to therapy with vincristine, cyclophosphamide and prednisolone and, he developed acute respiratory failure on the seventh month after admission. Although incidence of primary cardiac lymphoma is very low, it is necessary to investigate the mechanism of this disease in order to establish appropriate diagnostic and therapeutic approaches.
一名69岁男性,最初表现为腰痛,入院当天在进行磁共振成像(MRI)扫描时发生心力衰竭。胸部X线显示心脏扩大和双侧胸腔积液。胸部超声心动图和计算机断层扫描(CT)显示有一个巨大肿瘤包绕心脏,并伴有大量心包积液。心包穿刺抽取的积液细胞学检查结果与弥漫性大B细胞型非霍奇金淋巴瘤相符。由于腹部和骨盆的CT扫描结果为阴性,故考虑为原发性心脏淋巴瘤。尽管他对长春新碱、环磷酰胺和泼尼松龙治疗反应显著,但入院后第七个月出现了急性呼吸衰竭。虽然原发性心脏淋巴瘤的发病率很低,但有必要研究该疾病的发病机制,以建立适当的诊断和治疗方法。