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[一例刺激敏感性脊髓性肌阵挛病例]

[A case of stimulus-sensitive spinal myoclonus].

作者信息

Kono I, Matsuo Y, Nakajima K

机构信息

Department of Neurology, Ayabe Municipal Hospital.

出版信息

Rinsho Shinkeigaku. 1998 Jan;38(1):17-21.

PMID:9597904
Abstract

A 64-year-old man was admitted to our hospital because of a 2-year progression of muscular jerks on the bilateral thoracic and abdominal walls. Neurological examination was normal except for myoclonus localized in the bilateral Th5 to L1 segments. Myoclonus in this case was symmetrical and synchronous, and had a tendency to continue rhythmically. It was also segmental and considered to be spinal in origin. The interval between two adjacent myoclonic jerks was short when the amplitude and duration of the first myoclonus were high and long, respectively. We postulated that the activity of anterior horn cells at an impaired segment might be a factor that influences the resting time between jerks. A myoclonic jerk could be induced by a tendon tap given anywhere on this patient's body, with a latency ranging from 40 to 220 msec, irrespective of the sites of tapping. A long latency and polysynaptic reflex may participate in such stimulus sensitivity. The site of the reflex was probably above the motor nucleus of the trigeminal nerve, because jerks could be induced by jaw taps. Our observations support the theory that a spino-bulbo-spinal reflex is manifested at the impaired segment.

摘要

一名64岁男性因双侧胸腹壁肌肉抽搐2年进展而入住我院。神经系统检查除双侧胸5至腰1节段局限性肌阵挛外均正常。该病例的肌阵挛对称且同步,并有节律性持续的倾向。它也是节段性的,被认为起源于脊髓。当第一个肌阵挛的幅度和持续时间分别较高和较长时,两个相邻肌阵挛抽搐之间的间隔较短。我们推测受损节段前角细胞的活动可能是影响抽搐之间静息时间的一个因素。在该患者身体的任何部位进行肌腱叩击均可诱发肌阵挛抽搐,潜伏期为40至220毫秒,与叩击部位无关。长潜伏期和多突触反射可能参与这种刺激敏感性。反射部位可能在三叉神经运动核上方,因为叩击下颌可诱发抽搐。我们的观察结果支持在受损节段表现出脊髓-延髓-脊髓反射的理论。

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