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类似肚皮舞的脊髓性肌阵挛。

Spinal myoclonus resembling belly dance.

作者信息

Kono I, Ueda Y, Araki K, Nakajima K, Shibasaki H

机构信息

Department of Neurology and Gerontology, Kyoto Prefectural University of Medicine, Japan.

出版信息

Mov Disord. 1994 May;9(3):325-9. doi: 10.1002/mds.870090309.

Abstract

A 63-year-old man presented with an 11-month history of progressive myoclonus in the right abdominal wall. Administration of clonazepam reduced the frequency and amplitude. When the therapy was discontinued, the frequency and amplitude of the myoclonus increased, and synchronous and weak myoclonus also was observed in the left abdomen. The trunk was twisted just after the appearance of the abdominal myoclonus associated with myoclonic jerks spreading from the rostral to caudal paraspinal muscles. Later in the clinical course, the myoclonus became stimulus sensitive and was induced by tendon tap given anywhere on the body, with the latency ranging from 50 to 150 ms irrespective of the sites of tapping. Myoclonus seen in the abdominal wall was segmental and considered to be of spinal origin. The reflex myoclonus had a 150-ms refractory period. It can be postulated that increased excitability of anterior horn cells at a certain segment might make a spino-bulbo-spinal reflex manifest at the corresponding segment. This myoclonus is considered to be a new form of spinal reflex myoclonus, because the abdominal myoclonic jerk seems to trigger another myoclonic jerk involving the paraspinal muscles.

摘要

一名63岁男性,有11个月的右侧腹壁进行性肌阵挛病史。服用氯硝西泮后,肌阵挛的频率和幅度降低。当治疗中断时,肌阵挛的频率和幅度增加,并且在左腹部也观察到同步且微弱的肌阵挛。在与从脊髓上段向脊髓下段扩散的肌阵挛性抽搐相关的腹部肌阵挛出现后,躯干发生扭转。在临床病程后期,肌阵挛变得对刺激敏感,身体任何部位的腱反射均可诱发,无论叩击部位如何,潜伏期为50至150毫秒。腹壁出现的肌阵挛呈节段性,被认为起源于脊髓。反射性肌阵挛有150毫秒的不应期。可以推测,某一节段前角细胞兴奋性增加可能会使脊髓-延髓-脊髓反射在相应节段表现出来。这种肌阵挛被认为是一种新型的脊髓反射性肌阵挛,因为腹部肌阵挛性抽搐似乎会引发另一种涉及椎旁肌的肌阵挛性抽搐。

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