Fumagalli G, Ferrara A, Numeroso R
Minerva Med. 1976 Sep 22;67(44):2839-48.
The behaviour of partial tensions of respiratory gases and pH in the arterial blood was evaluated in anoxiaemic and hypercapnic (1st group) and hypo-eucapnic (IInd group) subjects undergoing oxygen therapy. The following phenomena were observed: 1) normalization in paO2 values in both groups; 2) statistically significant diminution in paCO2, especially as regards hypercapnic subjects; 3) statistically significant diminution in blood pH; 4) statistically significant diminution in bicarbonates. In the light of these findings, it is considered that other variables, such as the electrolytes, might play an important role in pH diminution during oxygen therapy and that further research should be carried out to look into the possibility.