来自海绵纲动物的三种新的manzamine同系物。
Three new manzamine congeners from amphimedon sponge.
作者信息
Watanabe D, Tsuda M, Kobayashi J
机构信息
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
出版信息
J Nat Prod. 1998 May;61(5):689-92. doi: 10.1021/np970564p.
PMID:9599281
Abstract
Three new manzamine congeners (1-3) have been isolated from the Okinawan marine sponge Amphimedon sp., and the structures, including relative stereochemistries, were elucidated on the basis of spectroscopic data. Absolute configuration at C-16 of 1 was determined by modified Mosher's method.
摘要
从冲绳海洋海绵Amphimedon sp.中分离出了三种新的manzamine类似物（1-3），并根据光谱数据阐明了其结构，包括相对立体化学结构。通过改良的Mosher方法确定了化合物1中C-16的绝对构型。
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