Shigemori H, Tenma M, Shimazaki K, Kobayashi J
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060, Japan.
J Nat Prod. 1998 May;61(5):696-8. doi: 10.1021/np980011u.
Two new diketopiperazines (1 and 2) with a d-cis-4-hydroxyproline residue, and orcinotriol (3), a new 1,3-dihydroxyphenol derivative, were isolated from cultured broth of the yeast Aureobasidium pullulans, which was isolated from an Okinawan marine sponge. The structures of the compounds, including their absolute stereochemistries, were determined by spectroscopic data and chemical means.
从冲绳海洋海绵中分离得到的酵母出芽短梗霉的培养液中,分离出了两种带有d-顺式-4-羟基脯氨酸残基的新型二酮哌嗪(1和2),以及一种新型1,3-二羟基苯酚衍生物苔黑酚三醇(3)。通过光谱数据和化学方法确定了这些化合物的结构,包括它们的绝对立体化学结构。