Fujishima H, Shimazaki J, Shinozaki N, Tsubota K
Department of Ophthalmology, Tokyo Dental College, Chiba, Japan.
Ophthalmic Surg Lasers. 1998 May;29(5):428-31.
Although trabeculectomy is an established surgical technique for glaucoma, in some cases it does not achieve a good filtering effect despite the use of mitomycin-C (MMC). The authors have developed a new surgical technique for uncontrollable glaucoma that uses amniotic membrane to prevent postoperative adhesion of conjunctiva and sclera. They performed trabeculectomy with a limbal-based conjunctival flap using 0.4 mg/ml of MMC for 2 minutes. Amniotic membrane was then placed under the scleral flap and sutured using 10-0 nylon. Among 14 eyes of 13 patients who underwent this procedure, intraocular pressure was controlled to less than 20 mm Hg after surgery in 13 eyes, including 3 eyes that underwent a second surgery with the same technique and 2 eyes that underwent laser trabeculoplasty. The authors' results suggest that this technique is efficacious for the reduction of intraocular pressure in high-risk glaucoma patients.
尽管小梁切除术是一种成熟的青光眼手术技术，但在某些情况下，即使使用丝裂霉素-C（MMC），也无法达到良好的滤过效果。作者开发了一种针对难治性青光眼的新手术技术，该技术使用羊膜来防止术后结膜和巩膜粘连。他们采用以角膜缘为基底的结膜瓣进行小梁切除术，使用0.4mg/ml的MMC 2分钟。然后将羊膜置于巩膜瓣下，用10-0尼龙线缝合。在接受该手术的13例患者的14只眼中，术后13只眼的眼压控制在20mmHg以下，其中包括3只采用相同技术进行二次手术的眼和2只接受激光小梁成形术的眼。作者的结果表明，该技术对于降低高危青光眼患者的眼压是有效的。
