Lund C, Braekken S K, Haggag K J, Røste L S, Russell D
Nevrologisk avdeling Rikshospitalet, Oslo.
Tidsskr Nor Laegeforen. 1998 Mar 30;118(9):1398-401.
The clinical diagnosis of brain embolism has traditionally been based on evidence suggesting a potential embolic source. However, it is now possible to detect circulating cerebral microemboli by means of transcranial Doppler ultrasound. We explain the theory behind microembolus detection, and discuss initial clinical experience of this method. During invasive cardiovascular investigations and surgery this method can warn the physician that microemboli are entering the cerebral circulation, and preventive measures can be taken. Cerebral microemboli are quite often detected in stroke prone patients, and their presence probably indicates increased risk of stroke. In the acute phase of ischemic stroke, microembolus detection may help to decide the etiology and the source of the emboli. When microemboli are detected in cases of acute embolic stroke, serial detections can be performed which, in future studies, might be of help when evaluating the effect of the treatment.
传统上，脑栓塞的临床诊断基于提示潜在栓子来源的证据。然而，现在可以通过经颅多普勒超声检测循环中的脑微栓子。我们解释了微栓子检测背后的理论，并讨论了该方法的初步临床经验。在侵入性心血管检查和手术期间，该方法可以提醒医生微栓子正在进入脑循环，从而可以采取预防措施。在易患中风的患者中经常检测到脑微栓子，其存在可能表明中风风险增加。在缺血性中风的急性期，微栓子检测可能有助于确定栓子的病因和来源。当在急性栓塞性中风病例中检测到微栓子时，可以进行系列检测，在未来的研究中，这可能有助于评估治疗效果。
