Bohr L, Greisen G
Neonatalklinikken GN, H:S Rigshospitalet, Juliane Marie Centret.
Ugeskr Laeger. 1998 May 4;160(19):2845-50.
Reviewing the literature published during the last 30 years we found comparable systematic studies of outcome for 1042 term infants born alive after likely intrapartum hypoxia-ischaemia. Fifty-two percent had no sequelae, 8% had developmental delay without associated handicaps, 4% had a single handicap, 11% were multihandicapped and 14% were dead as a consequence of the intrapartum hypoxia-ischaemia. The frequency of single handicaps exceeded the frequency found among the controls and in population studies. The frequency of children with developmental delay did not differ from that found among the controls. Outcome is closely related to the severity of hypoxic-ischaemic encephalopathy in the newborn.
回顾过去30年发表的文献,我们发现了对1042名可能在分娩期发生缺氧缺血后存活的足月儿结局的类似系统研究。52%的患儿无后遗症,8%有发育迟缓但无相关残疾,4%有单一残疾,11%为多重残疾,14%因分娩期缺氧缺血而死亡。单一残疾的发生率超过了对照组和人群研究中的发生率。发育迟缓儿童的发生率与对照组无差异。结局与新生儿缺氧缺血性脑病的严重程度密切相关。