Nakamura S, Yoshida G, Takezawa Y, Sato T
Tohoku J Exp Med. 1976 Aug;119(4):345-52. doi: 10.1620/tjem.119.345.
Ethanol-1-14C method for the measurement of intrahepatic shunted blood flow was compared with the method of continuous infusion of D-galactose-1-14C. In controls, in chronic hepatitis, and in hepatic cirrhosis, per cent intrahepatic shunt measured by the ethanol-1-14C- method was about a half or one-third of that measured by the D-galactose-1-14C method. Study of radioactivity-dye concentration ratio of the blood sampled from the inferior vena cava showed that per cent intrahepatic shunt was underestimated by the ethanol-1-14C method because of permeability of ethanol-1-14C through the capillaries. In patients with hepatic carcinoma, in whom the carcinomatous tissue was supplied mainly by the hepatic artery, there was no significant difference in per cent intrahepatic shunt between both methods.
将用于测量肝内分流血流量的乙醇-1-14C法与连续输注D-半乳糖-1-14C法进行了比较。在对照组、慢性肝炎患者和肝硬化患者中，用乙醇-1-14C法测得的肝内分流百分比约为用D-半乳糖-1-14C法测得的一半或三分之一。对从下腔静脉采集的血液进行放射性-染料浓度比研究表明，由于乙醇-1-14C可透过毛细血管，乙醇-1-14C法低估了肝内分流百分比。在主要由肝动脉供血的肝癌患者中，两种方法测得的肝内分流百分比无显著差异。
