Bruera E, Pruvost M, Schoeller T, Montejo G, Watanabe S
Palliative Care Unit, Grey Nuns Community Hospital & Health Care Centre, Edmonton, Alberta, Canada.
J Pain Symptom Manage. 1998 Apr;15(4):216-9. doi: 10.1016/s0885-3924(97)00367-9.
In a prospective, open study, 78 patients with terminal cancer received proctoclysis (rectal hydration) in four different centers. In all cases, a #22 French nasogastric catheter was inserted approximately 40 cm into the rectum and an infusion of normal saline (2 cases) or tap water (76 cases) was administered at a rate of 250 +/- 63 cc/hr. Hydration was maintained for 15 +/- 8 days. The main reason for discontinuation of hydration was death (60 cases). The mean visual analogue score for discomfort after infusion (0 = no discomfort, 100 = worst possible discomfort) was 19 +/- 14. The costs of proctoclysis was estimated at Can$0.08 compared with Can$4.56 per day for hypodermoclysis, and Can$2.78 per day for intravenous hydration. Our results suggest that proctoclysis is a safe, effective, and low-cost technique for the delivery of hydration in terminally ill cancer patients.
在一项前瞻性开放研究中，78例晚期癌症患者在四个不同中心接受了直肠灌洗（直肠补液）。所有病例均插入一根22号法国鼻胃管至直肠约40厘米处，并以250±63毫升/小时的速率输注生理盐水（2例）或自来水（76例）。补液持续15±8天。停止补液的主要原因是死亡（60例）。输注后不适的平均视觉模拟评分（0 = 无不适，100 = 可能的最严重不适）为19±14。直肠灌洗的成本估计为0.08加元，皮下补液每天4.56加元，静脉补液每天2.78加元。我们的结果表明，直肠灌洗是一种用于终末期癌症患者补液的安全、有效且低成本的技术。
