Bruera E, Belzile M, Watanabe S, Fainsinger R L
Division of Palliative Care Medicine, Edmonton General Hospital, Alberta, Canada.
Support Care Cancer. 1996 Mar;4(2):147-50. doi: 10.1007/BF01845764.
In this retrospective study we reviewed the volume and modality of hydration of consecutive series of terminal cancer patients in two different settings. In a palliative care unit 203/290 admitted patients received subcutaneous hydration for 12 +/- 8 days at a daily volume of 1015 +/- 135 ml/day. At the cancer center, 30 consecutive similar patients received intravenous hydration for 11.5 +/- 5 days (P > 0.2) but at a daily volume of 2080 +/- 720 ml/day (P < 0.001). None of the palliative care unit patients required discontinuation of hydration because of complications. Hypodermoclysis was administered mainly as a continuous infusion, an overnight infusion, or in one to three 1-h boluses in 62 (31%), 98 (48%) and 43 (21%) patients, respectively. Our findings suggest that, in some settings, patients may be receiving excessive volumes of hydration by less comfortable routes such as the intravenous route. Increased education and research in this area are badly needed.
在这项回顾性研究中，我们在两种不同环境下回顾了连续系列终末期癌症患者的补液量和补液方式。在一家姑息治疗病房，290名入院患者中有203名接受了皮下补液，为期12±8天，每日补液量为1015±135毫升/天。在癌症中心，30名连续的类似患者接受了静脉补液，为期11.5±5天（P>0.2），但每日补液量为2080±720毫升/天（P<0.001）。姑息治疗病房的患者均未因并发症而需要停止补液。皮下输液主要分别以持续输注、夜间输注或1至3次1小时推注的方式给予，接受这三种方式的患者分别有62名（31%）、98名（48%）和43名（21%）。我们的研究结果表明，在某些情况下，患者可能通过静脉等不太舒适途径接受了过量补液。该领域急需加强教育和研究。
