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[溃疡性结肠炎中的骨骼变化]

[Bone changes in ulcerative colitis].

作者信息

Huorka M, Payer J, Duris I, Killinger Z, Kratochvíl'ová H, Ondrejka P

机构信息

I. interná klinika FN, Bratislava.

出版信息

Vnitr Lek. 1997 Apr;43(4):214-6.

PMID:9601838
Abstract

One of the complications of ulcerative colitis with frequent relapses is mineral deficiency (potassium, calcium, magnesium and phosphorus). The objective of the present work is to examine the bone density and laboratory parameters of bone metabolism in 25 patients with a medium severe and severe form of ulcerative colitis. In patients with ulcerative colitis a significantly reduced bone density was found in the era of neck of the femur (p < 0.05), a a non-significantly reduction of the bone density in the era of the lumbar vertebrae and an elevated level of osteocalcin (p < 0.05). These findings indicate a higher prevalence of bone changes in patients with ulcerative colitis. Early detection of bone changes makes adequate prevention and treatment of bone complications possible.

摘要

溃疡性结肠炎频繁复发的并发症之一是矿物质缺乏(钾、钙、镁和磷)。本研究的目的是检查25例中度至重度溃疡性结肠炎患者的骨密度和骨代谢实验室参数。在溃疡性结肠炎患者中,发现股骨颈部位骨密度显著降低(p < 0.05),腰椎部位骨密度有非显著性降低,骨钙素水平升高(p < 0.05)。这些发现表明溃疡性结肠炎患者骨改变的患病率较高。早期发现骨改变使得对骨并发症进行充分的预防和治疗成为可能。

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