Krajícková D, Peregrin J H, Stríbrná J, Belán A, Vítko S
Základna radiodiagnostiky a intervencní radiologie IKEM, Praha.
Vnitr Lek. 1997 Dec;43(12):775-80.
The objective of the work was to evaluate the contribution of percutaneous transluminal angioplasty (PTA) to treatment of hypertension and the graft function of a transplanted kidney. Angioplasty of the graft artery was performed in 39 patients. Technical success rate: 85%.
13%--in particular during the first years after introduction of the method. Twenty seven patients were followed up on a long-term basis. Changes of the median arterial pressure (MAP) were evaluated as well as glomerular filtration (GF) assessed by creatinine clearance. Mean values: [table: see text] A statistically significant (p < 0.01) reduction of the median arterial pressure (drop by > 10 mm Hg) along with reduction of the number of antihypertensive drugs was recorded in 70% of the patients during the first year and in 80% kidney recipients in investigations extending beyond one year. A significant increase of glomerular filtration (by > 20%) was found in 40% of the patients, on average the rise was insignificant. During the follow up period 13 kidney recipients were transferred to a dialyzation programme due to failure of the grafts as a result of rejection.
Percutaneous transluminal angioplasty of a stenosis of the graft artery is the method of first choice in the treatment of hypertension. It is of fundamental importance also in rare cases in order to preserve or improve graft function and thus delay dialyzation treatment.
本研究的目的是评估经皮腔内血管成形术（PTA）对高血压治疗及移植肾移植肾功能的贡献。对39例患者进行了移植肾动脉血管成形术。技术成功率：85%。
13%——尤其是在该方法应用后的最初几年。对27例患者进行了长期随访。评估了平均动脉压（MAP）的变化以及通过肌酐清除率评估的肾小球滤过率（GF）。平均值：[表格：见原文]。在第一年，70%的患者记录到平均动脉压有统计学意义的降低（下降>10 mmHg），同时抗高血压药物数量减少；在超过一年的研究中，80%的肾移植受者出现这种情况。40%的患者肾小球滤过率有显著增加（增加>20%），平均升高无统计学意义。在随访期间，13例肾移植受者因移植肾排斥失败而转入透析治疗。
移植肾动脉狭窄的经皮腔内血管成形术是治疗高血压的首选方法。在罕见情况下，为了保留或改善移植肾功能从而延迟透析治疗，该方法也至关重要。
