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肠套叠的超声检查及临床预测指标

Ultrasonographic and clinical predictors of intussusception.

作者信息

Harrington L, Connolly B, Hu X, Wesson D E, Babyn P, Schuh S

机构信息

Department of Diagnostic Imaging, Hospital for Sick Children, University of Toronto, Ontario, Canada.

出版信息

J Pediatr. 1998 May;132(5):836-9. doi: 10.1016/s0022-3476(98)70314-2.

Abstract

OBJECTIVE

The objective of this study was to determine the positive and negative clinical predictors of intussusception and the correlation of ultrasonography and air enema in establishing this diagnosis.

STUDY DESIGN

This was a prospective descriptive cohort study.

SETTING

This study was performed in a tertiary care pediatric emergency department.

PARTICIPANTS

Eighty-eight of 245 candidates were assessed for clinical predictors of intussusception. All 245 cases were examined for correlation between ultrasonography and air enema.

INTERVENTIONS

A questionnaire, ultrasonography, and air enema were used.

RESULTS

Thirty-five of the 88 patients assessed for clinical predictors were positive for intussusception. Significant positive predictors were right upper quadrant abdominal mass (positive predictive value [PPV] 94%), gross blood in stool (PPV 80%), blood on rectal examination (PPV 78%), the triad of intermittent abdominal pain, vomiting, and right upper quadrant abdominal mass (PPV 93%, p = 0.0001), and the triad with occult or gross blood per rectum (PPV 100%, p = not significant). Significant negative predictors were a combination of > or = 3 of 10 clinically significant negative features (negative predictive value 77%, p = 0.035). Of the total 245 cases, intussusception (as confirmed by doughnut, target, or pseudokidney sign) was ruled out by ultrasonography in 97.4%. Alternate ultrasound findings comprised 27% of negative cases.

CONCLUSIONS

Excellent positive predictors of intussusception were identified prospectively. Although no reliable negative predictors were found, patients at low risk may be screened by ultrasonography.

摘要

目的

本研究的目的是确定肠套叠的临床阳性和阴性预测指标,以及超声检查和气灌肠在确立该诊断中的相关性。

研究设计

这是一项前瞻性描述性队列研究。

研究地点

本研究在一家三级护理儿科急诊科进行。

研究对象

245名候选者中的88名接受了肠套叠临床预测指标的评估。所有245例病例均接受了超声检查和气灌肠相关性的检查。

干预措施

采用问卷调查、超声检查和气灌肠。

结果

在接受临床预测指标评估的88例患者中,35例肠套叠呈阳性。显著的阳性预测指标为右上腹肿块(阳性预测值[PPV]94%)、大便带血(PPV 80%)、直肠指检有血(PPV 78%)、间歇性腹痛、呕吐和右上腹肿块三联征(PPV 93%,p = 0.0001),以及伴有直肠潜血或肉眼血便的三联征(PPV 100%,p =无显著性差异)。显著的阴性预测指标为10项临床显著阴性特征中≥3项的组合(阴性预测值77%,p = 0.035)。在全部245例病例中,超声检查排除了97.4%的肠套叠(通过“甜甜圈”征、“靶”征或“假肾”征确诊)。其他超声检查结果占阴性病例的27%。

结论

前瞻性地确定了肠套叠出色的阳性预测指标。虽然未发现可靠的阴性预测指标,但低风险患者可通过超声检查进行筛查。

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