Harrington L, Connolly B, Hu X, Wesson D E, Babyn P, Schuh S
Department of Diagnostic Imaging, Hospital for Sick Children, University of Toronto, Ontario, Canada.
J Pediatr. 1998 May;132(5):836-9. doi: 10.1016/s0022-3476(98)70314-2.
The objective of this study was to determine the positive and negative clinical predictors of intussusception and the correlation of ultrasonography and air enema in establishing this diagnosis.
This was a prospective descriptive cohort study.
This study was performed in a tertiary care pediatric emergency department.
Eighty-eight of 245 candidates were assessed for clinical predictors of intussusception. All 245 cases were examined for correlation between ultrasonography and air enema.
A questionnaire, ultrasonography, and air enema were used.
Thirty-five of the 88 patients assessed for clinical predictors were positive for intussusception. Significant positive predictors were right upper quadrant abdominal mass (positive predictive value [PPV] 94%), gross blood in stool (PPV 80%), blood on rectal examination (PPV 78%), the triad of intermittent abdominal pain, vomiting, and right upper quadrant abdominal mass (PPV 93%, p = 0.0001), and the triad with occult or gross blood per rectum (PPV 100%, p = not significant). Significant negative predictors were a combination of > or = 3 of 10 clinically significant negative features (negative predictive value 77%, p = 0.035). Of the total 245 cases, intussusception (as confirmed by doughnut, target, or pseudokidney sign) was ruled out by ultrasonography in 97.4%. Alternate ultrasound findings comprised 27% of negative cases.
Excellent positive predictors of intussusception were identified prospectively. Although no reliable negative predictors were found, patients at low risk may be screened by ultrasonography.
本研究的目的是确定肠套叠的临床阳性和阴性预测指标,以及超声检查和气灌肠在确立该诊断中的相关性。
这是一项前瞻性描述性队列研究。
本研究在一家三级护理儿科急诊科进行。
245名候选者中的88名接受了肠套叠临床预测指标的评估。所有245例病例均接受了超声检查和气灌肠相关性的检查。
采用问卷调查、超声检查和气灌肠。
在接受临床预测指标评估的88例患者中,35例肠套叠呈阳性。显著的阳性预测指标为右上腹肿块(阳性预测值[PPV]94%)、大便带血(PPV 80%)、直肠指检有血(PPV 78%)、间歇性腹痛、呕吐和右上腹肿块三联征(PPV 93%,p = 0.0001),以及伴有直肠潜血或肉眼血便的三联征(PPV 100%,p =无显著性差异)。显著的阴性预测指标为10项临床显著阴性特征中≥3项的组合(阴性预测值77%,p = 0.035)。在全部245例病例中,超声检查排除了97.4%的肠套叠(通过“甜甜圈”征、“靶”征或“假肾”征确诊)。其他超声检查结果占阴性病例的27%。
前瞻性地确定了肠套叠出色的阳性预测指标。虽然未发现可靠的阴性预测指标,但低风险患者可通过超声检查进行筛查。