Ikawa M, Ikawa K, Horiuchi H
Department of Endodontics and Periodontics, Tohoku University School of Dentistry, Sendai, Japan.
Arch Oral Biol. 1998 Feb;43(2):127-32. doi: 10.1016/s0003-9969(97)00103-9.
The purpose of this study was to compare the state of the microcirculation in healthy gingiva with that in untreated, inflamed gingiva in humans. Reflection photoplethysmography (RP) was used to record blood flow from 13 clinically healthy, attached gingival sites in seven adults and 11 inflamed sites in seven patients. Changes in the pulse amplitude of the RP signal were measured before and after application of thermal (cold and hot water) and mechanical (brushing) stimuli to the gingiva. Hot water and brushing, but not cold water, produced a significant increase in the pulse amplitude in healthy gingiva (p < 0.05, Friedman analysis and Student-Newman Keuls test). None of the stimuli produced a significant change in inflamed gingiva. In neither group of participants was there a significant correlation (Spearman rank correlation coefficient) between vascular responsiveness and age. The results indicated that vasomotor control may be impaired in inflamed gingiva.
本研究的目的是比较人类健康牙龈与未经治疗的炎症牙龈的微循环状态。采用反射式光电容积描记法（RP）记录7名成年人13个临床健康的附着龈部位以及7名患者11个炎症部位的血流情况。在对牙龈施加热刺激（冷水和热水）和机械刺激（刷牙）之前和之后，测量RP信号的脉搏振幅变化。热水和刷牙可使健康牙龈的脉搏振幅显著增加（p < 0.05，Friedman分析和Student-Newman Keuls检验），但冷水不会。所有刺激均未使炎症牙龈产生显著变化。在两组参与者中，血管反应性与年龄之间均无显著相关性（Spearman等级相关系数）。结果表明，炎症牙龈的血管舒缩控制可能受损。
