外周B细胞的B细胞受体调控
B-cell receptor regulation of peripheral B cells.
作者信息
MacLennan I C
机构信息
Department of Immunology, University of Birmingham Medical School, UK.
出版信息
Curr Opin Immunol. 1998 Apr;10(2):220-5. doi: 10.1016/s0952-7915(98)80252-5.
PMID:9602312
Abstract
Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing cells.
摘要
最近的研究表明，未成熟B细胞与再循环B细胞竞争生存信号。这些通过抗原的B细胞受体传递的信号，诱导未成熟细胞分化为再循环细胞，并维持再循环细胞的存活。它们不会诱导增殖或分化为产生抗体的细胞。
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