伴有轻链细胞外沉积的肺孤立性浆细胞瘤：一例报告并文献复习
Solitary plasmacytoma of the lung with light chain extracellular deposits: a case report and review of the literature.
作者信息
Piard F, Yaziji N, Jarry O, Assem M, Martin L, Bernard A, Jacquot J P, Justrabo E
机构信息
Department of Pathology, Dijon University Hospital, France.
出版信息
Histopathology. 1998 Apr;32(4):356-61. doi: 10.1046/j.1365-2559.1998.00393.x.
AIMS
We present the clinical and histopathological findings of an unusual pulmonary plasmacytoma associated with light chain deposits.
METHODS AND RESULTS
The tumour was located in the main left stem bronchus 40 mm from the carina. Histologically, it was composed of sheets of well differentiated plasma cells. Large extracellular deposits of amorphous material were observed in the tumour. These deposits were Congo red negative and contained kappa light chains. They were electron dense granular and non-filamentous. No plasmacytosis was identified by bone marrow biopsy and no monoclonal spike was shown by serum and urine electrophoresis.
CONCLUSIONS
Our case is unusual in being endobronchial and showing light chain deposition.
目的
我们展示了一例与轻链沉积相关的罕见肺浆细胞瘤的临床和组织病理学表现。
方法与结果
肿瘤位于距隆突40毫米的左主支气管。组织学上，它由成片的高分化浆细胞组成。在肿瘤中观察到大量无定形物质的细胞外沉积。这些沉积物刚果红染色阴性，含有κ轻链。它们是电子致密颗粒状且无丝状结构。骨髓活检未发现浆细胞增多，血清和尿电泳未显示单克隆峰。
结论
我们的病例不同寻常之处在于它位于支气管内且有轻链沉积。
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