Tomé J, Carsi B, García-Fernández C, Marco F, López-Durán Stern L
Department of Orthopaedics, Hospital Clinico San Carlos, Madrid, Spain.
Clin Orthop Relat Res. 1998 May(350):51-5.
A retrospective study is presented of 14 patients with pathologic fractures of the humerus (12 established, two impending) treated with Seidel nailing from 1988 through 1995 in the authors' institution. There were nine women and five men whose average age was 59.5 years. Breast, prostate, and kidney hypernephroma accounted for the majority of the primary lesions. All but one lesion were located in the middle shaft of the humerus. Ten lesions were considered large (> 5 cm long). In five cases an open curettage and allografting were done. Early pain relief was successful in 85% of the patients. The worst complication found was definite nerve palsy in two (14.28%) patients. Ten fractures healed and two failed to heal. Two thirds of the patients had good functional results. The average survival was 12 months. Intramedullary fixation of pathologic fractures improves the quality of life by controlling pain for most patients.
本文回顾性研究了1988年至1995年在作者所在机构采用塞德尔髓内钉治疗的14例肱骨病理性骨折患者（12例已确诊，2例为即将发生骨折）。其中女性9例，男性5例，平均年龄59.5岁。原发病变多数为乳腺癌、前列腺癌和肾肾上腺瘤。除1例病变外，所有病变均位于肱骨干中部。10个病变被认为较大（长度>5 cm）。5例患者进行了切开刮除和同种异体骨移植。85%的患者早期疼痛缓解成功。发现的最严重并发症是2例（14.28%）患者出现明确的神经麻痹。10例骨折愈合，2例未愈合。三分之二的患者功能结果良好。平均生存期为12个月。病理性骨折的髓内固定通过控制大多数患者的疼痛提高了生活质量。
