Fukuhara K, Urano Y, Akaike M, Ahsan K, Arase S
Department of Dermatology, School of Medicine, University of Tokushima, Japan.
Br J Dermatol. 1998 Feb;138(2):329-33. doi: 10.1046/j.1365-2133.1998.02085.x.
A 40-year-old Japanese man with psoriatic arthritis (PA) involving the spine, sacroiliac and peripheral joints presented with dyspnoea and ankle oedema. Blood pressure was 180/110 and 114/80 mmHg in the right and left upper arms, respectively. Examinations showed left ventricular dilatation and diffuse hypokinesis of the left ventricle, with no involvement of the coronary arteries. Aortography detected total occlusion of the left subclavian artery and stenosis of the origin at the right renal artery. Dilated cardiomyopathy and Takayasu's arteritis associated with PA was diagnosed. A few cases of PA have been reported in association with cardiovascular diseases, but the association of these three diseases has not been documented in the literature to date. Dermatologists need to be aware of cardiovascular manifestations in patients with PA, because cardiovascular diseases are not rare in other seronegative spondyloarthropathies.
一名40岁的日本男性,患有累及脊柱、骶髂关节和外周关节的银屑病关节炎(PA),出现呼吸困难和踝关节水肿。右上肢血压为180/110 mmHg,左上肢血压为114/80 mmHg。检查显示左心室扩张和左心室弥漫性运动减弱,冠状动脉未受累。主动脉造影发现左锁骨下动脉完全闭塞,右肾动脉起始处狭窄。诊断为扩张型心肌病和与PA相关的高安动脉炎。此前已有少数PA与心血管疾病相关的病例报道,但这三种疾病的关联至今尚未见文献记载。皮肤科医生需要注意PA患者的心血管表现,因为心血管疾病在其他血清阴性脊柱关节病中并不罕见。